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Synthesis and Preliminary Chemotherapeutic Evaluation of the Fully C-Linked Glucuronide of N-(4-Hydroxyphenyl) retinamide (4-HPR)
All-trans retinoic acid (atRA) analogues such as N-(4-hydroxyphenyl) retinamide (4-HPR) are effective chemopreventive and chemotherapeutic agents but their utility has been hampered by dose-limiting side effects. The glucuronide derivatives of 4-HPR, the oxygen-linked 4-HPROG and the carbon-linked 4...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1459539/ https://ncbi.nlm.nih.gov/pubmed/16412653 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2005.12.044 |
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