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Oxidative stress affects processing of amyloid precursor protein in vascular endothelial cells

BACKGROUND: Oxidative stress is thought to be a key player in the pathogenesis of neurodegenerative dementia, including Alzheimer’s disease (AD). It has been assumed that oxidative stress contributes to the ß-amyloid deposition in cerebral blood vessels. METHODS: In order to prove this hypothesis, w...

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Vydáno v:PLoS One
Hlavní autoři: Muche, Abebe, Arendt, Thomas, Schliebs, Reinhard
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5472258/
https://ncbi.nlm.nih.gov/pubmed/28617802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0178127
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