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Effects of oxidative stress on amyloid precursor protein processing in rat and human platelets

Alzheimer’s disease (AD) is the most common neurodegenerative illness affecting the elderly and is characterized by beta-amyloid (Aβ) deposition in the brain (plaques) and in microvessels (Aβ-angiopathy). The reasons for Aβ deposition are not clear, but an impaired clearance of Aβ at the blood-brain...

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Detalhes bibliográficos
Publicado no:Platelets
Main Authors: EHRLICH, DANIELA, HOCHSTRASSER, TANJA, HUMPEL, CHRISTIAN
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4311141/
https://ncbi.nlm.nih.gov/pubmed/22385218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/09537104.2012.661104
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