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A General Approach to Testing for Pleiotropy with Rare and Common Variants
Through genome-wide association studies, numerous genes have been shown to be associated with multiple phenotypes. To determine the overlap of genetic susceptibility of correlated phenotypes, one can apply multivariate regression or dimension reduction techniques, such as principal components analys...
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| Publicado no: | Genet Epidemiol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5472207/ https://ncbi.nlm.nih.gov/pubmed/27900789 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.22011 |
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