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eQTL mapping of rare variant associations using RNA-seq data: An evaluation of approaches

Expression quantitative trait loci (eQTL) provide insight on transcription regulation and illuminate the molecular basis of phenotypic outcomes. High-throughput RNA sequencing (RNA-seq) is becoming a popular technique to measure gene expression abundance. Traditional eQTL mapping methods for microar...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Lutz, Sharon Marie, Thwing, Annie, Fingerlin, Tasha
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6776318/
https://ncbi.nlm.nih.gov/pubmed/31581212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0223273
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