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Simple Fibroblast-Based Assay To Test the Pyrazinamide Susceptibility of Mycobacterium tuberculosis

A simple fibroblast-based assay (SFA) was found to be efficient in evaluating the susceptibilities of clinical isolates of Mycobacterium tuberculosis to pyrazinamide (PZA). Forty-five clinical isolates were examined. The MICs of PZA for susceptible strains in an SFA were between 3.13 and 12.5 μg/ml,...

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Detalhes bibliográficos
Main Authors: Takii, Takemasa, Hamasaki, Sonomi, Hirano, Kazue, Abe, Chiyoji, Onozaki, Kikuo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC547215/
https://ncbi.nlm.nih.gov/pubmed/15673774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.2.804-807.2005
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