A controlled-release mitochondrial protonophore reverses hypertriglyceridemia, nonalcoholic steatohepatitis, and diabetes in lipodystrophic mice

Lipodystrophy is a rare disorder characterized by complete or partial loss of adipose tissue. Patients with lipodystrophy exhibit hypertriglyceridemia, severe insulin resistance, type 2 diabetes, and nonalcoholic steatohepatitis (NASH). Efforts to ameliorate NASH in lipodystrophies with pharmacologi...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Abulizi, Abudukadier, Perry, Rachel J., Camporez, João Paulo G., Jurczak, Michael J., Petersen, Kitt Falk, Aspichueta, Patricia, Shulman, Gerald I.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5471523/
https://ncbi.nlm.nih.gov/pubmed/28330852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201700001R
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados