Compensatory and decompensatory alterations in cardiomyocyte Ca(2+) dynamics in hearts with diastolic dysfunction following aortic banding

KEY POINTS: At the cellular level cardiac hypertrophy causes remodelling, leading to changes in ionic channel, pump and exchanger densities and kinetics. Previous studies have focused on quantifying changes in channels, pumps and exchangers without quantitatively linking these changes with emergent...

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Detalhes bibliográficos
Publicado no:J Physiol
Main Authors: Gattoni, Sara, Røe, Åsmund Treu, Aronsen, Jan Magnus, Sjaastad, Ivar, Louch, William E., Smith, Nicolas P., Niederer, Steven A.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Cardiac Excitation Contraction Coupling and Calcium Signalling
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5471387/
https://ncbi.nlm.nih.gov/pubmed/28542952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP273879
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