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Increased passive stiffness promotes diastolic dysfunction despite improved Ca(2+) handling during left ventricular concentric hypertrophy

AIMS: Concentric hypertrophy following pressure-overload is linked to preserved systolic function but impaired diastolic function, and is an important substrate for heart failure with preserved ejection fraction. While increased passive stiffness of the myocardium is a suggested mechanism underlying...

詳細記述

保存先:
書誌詳細
出版年:Cardiovasc Res
主要な著者: Røe, Åsmund T., Aronsen, Jan Magnus, Skårdal, Kristine, Hamdani, Nazha, Linke, Wolfgang A., Danielsen, Håvard E., Sejersted, Ole M., Sjaastad, Ivar, Louch, William E.
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5852536/
https://ncbi.nlm.nih.gov/pubmed/28472418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvx087
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