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Increased passive stiffness promotes diastolic dysfunction despite improved Ca(2+) handling during left ventricular concentric hypertrophy
AIMS: Concentric hypertrophy following pressure-overload is linked to preserved systolic function but impaired diastolic function, and is an important substrate for heart failure with preserved ejection fraction. While increased passive stiffness of the myocardium is a suggested mechanism underlying...
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| Publicado no: | Cardiovasc Res |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5852536/ https://ncbi.nlm.nih.gov/pubmed/28472418 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvx087 |
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