Mechanism of early dissemination and metastasis in Her2(+) mammary cancer

Metastasis is the leading cause of cancer-related deaths; metastatic lesions develop from disseminated cancer cells (DCCs) that can remain dormant(1). Metastasis-initiating cells are thought to originate from a subpopulation present in progressed, invasive tumours(2). However, DCCs detected in patie...

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Udgivet i:Nature
Main Authors: Harper, Kathryn L., Sosa, Maria Soledad, Entenberg, David, Hosseini, Hedayatollah, Cheung, Julie F., Nobre, Rita, Avivar-Valderas, Alvaro, Nagi, Chandandaneep, Girnius, Nomeda, Davis, Roger J., Farias, Eduardo F., Condeelis, John, Klein, Christoph A., Aguirre-Ghiso, Julio A.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5471138/
https://ncbi.nlm.nih.gov/pubmed/27974798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature20609
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