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Diagnostic Yield of Clinical Tumor and Germline Whole-Exome Sequencing for Children With Solid Tumors
IMPORTANCE: Whole-exome sequencing (WES) has the potential to reveal tumor and germline mutations of clinical relevance, but the diagnostic yield for pediatric patients with solid tumors is unknown. OBJECTIVE: To characterize the diagnostic yield of combined tumor and germline WES for children with...
में बचाया:
में प्रकाशित: | JAMA Oncol |
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मुख्य लेखकों: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
स्वरूप: | Artigo |
भाषा: | Inglês |
प्रकाशित: |
2016
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विषय: | |
ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5471125/ https://ncbi.nlm.nih.gov/pubmed/26822237 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2015.5699 |
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