Small molecules targeting histone demethylase genes (KDMs) inhibit growth of temozolomide-resistant glioblastoma cells

In glioblastoma several histone demethylase genes (KDM) are overexpressed compared to normal brain tissue and the development of Temozolomide (TMZ) resistance is accompanied by the transient further increased expression of KDM5A and other KDMs following a mechanism that we defined as “epigenetic res...

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Detaylı Bibliyografya
Yayımlandı:Oncotarget
Asıl Yazarlar: Banelli, Barbara, Daga, Antonio, Forlani, Alessandra, Allemanni, Giorgio, Marubbi, Daniela, Pistillo, Maria Pia, Profumo, Aldo, Romani, Massimo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2017
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5471020/
https://ncbi.nlm.nih.gov/pubmed/28432280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16820
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