Small molecules targeting histone demethylase genes (KDMs) inhibit growth of temozolomide-resistant glioblastoma cells

In glioblastoma several histone demethylase genes (KDM) are overexpressed compared to normal brain tissue and the development of Temozolomide (TMZ) resistance is accompanied by the transient further increased expression of KDM5A and other KDMs following a mechanism that we defined as “epigenetic res...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Oncotarget
Egile Nagusiak: Banelli, Barbara, Daga, Antonio, Forlani, Alessandra, Allemanni, Giorgio, Marubbi, Daniela, Pistillo, Maria Pia, Profumo, Aldo, Romani, Massimo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Impact Journals LLC 2017
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5471020/
https://ncbi.nlm.nih.gov/pubmed/28432280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16820
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