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Factors affecting the loss of MED12-mutated leiomyoma cells during in vitro growth

Uterine leiomyomas (UL) are the most prevalent symptomatic human tumors at all and somatic mutations of the gene encoding mediator subcomplex 12 (MED12) constitute the most frequent driver mutations in UL. Recently, a rapid loss of mutated cells during in vitro growth of UL-derived cell cultures was...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Bloch, Jeannine, Holzmann, Carsten, Koczan, Dirk, Helmke, Burkhard Maria, Bullerdiek, Jörn
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5471009/
https://ncbi.nlm.nih.gov/pubmed/28410233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16711
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