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Factors affecting the loss of MED12-mutated leiomyoma cells during in vitro growth

Uterine leiomyomas (UL) are the most prevalent symptomatic human tumors at all and somatic mutations of the gene encoding mediator subcomplex 12 (MED12) constitute the most frequent driver mutations in UL. Recently, a rapid loss of mutated cells during in vitro growth of UL-derived cell cultures was...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Bloch, Jeannine, Holzmann, Carsten, Koczan, Dirk, Helmke, Burkhard Maria, Bullerdiek, Jörn
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5471009/
https://ncbi.nlm.nih.gov/pubmed/28410233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16711
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