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Factors affecting the loss of MED12-mutated leiomyoma cells during in vitro growth

Uterine leiomyomas (UL) are the most prevalent symptomatic human tumors at all and somatic mutations of the gene encoding mediator subcomplex 12 (MED12) constitute the most frequent driver mutations in UL. Recently, a rapid loss of mutated cells during in vitro growth of UL-derived cell cultures was...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Bloch, Jeannine, Holzmann, Carsten, Koczan, Dirk, Helmke, Burkhard Maria, Bullerdiek, Jörn
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5471009/
https://ncbi.nlm.nih.gov/pubmed/28410233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16711
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