Nalaganje...
Type I interferons suppress viral replication but contribute to T cell depletion and dysfunction during chronic HIV-1 infection
The direct link between sustained type I interferon (IFN-I) signaling and HIV-1–induced immunopathogenesis during chronic infection remains unclear. Here we report studies using a monoclonal antibody to block IFN-α/β receptor 1 (IFNAR1) signaling during persistent HIV-1 infection in humanized mice (...
Shranjeno v:
| izdano v: | JCI Insight |
|---|---|
| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Clinical Investigation
2017
|
| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5470878/ https://ncbi.nlm.nih.gov/pubmed/28614789 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.94366 |
| Oznake: |
Označite
Brez oznak, prvi označite!
|