Blocking type I interferon signaling enhances T cell recovery and reduces HIV-1 reservoirs

Despite the efficient suppression of HIV-1 replication that can be achieved with combined antiretroviral therapy (cART), low levels of type I interferon (IFN-I) signaling persist in some individuals. This sustained signaling may impede immune recovery and foster viral persistence. Here we report stu...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Cheng, Liang, Ma, Jianping, Li, Jingyun, Li, Dan, Li, Guangming, Li, Feng, Zhang, Qing, Yu, Haisheng, Yasui, Fumihiko, Ye, Chaobaihui, Tsao, Li-Chung, Hu, Zhiyuan, Su, Lishan, Zhang, Liguo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5199717/
https://ncbi.nlm.nih.gov/pubmed/27941247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI90745
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