IL-4Rα on dendritic cells in neonates and Th2 immunopathology in respiratory syncytial virus infection

Respiratory syncytial virus (RSV) is one of the leading causes of bronchiolitis in children, and severe RSV infection early in life has been associated with asthma development. Using a neonatal mouse model, we have shown that down-regulation of IL-4 receptor α (IL-4Rα) with antisense oligonucleotide...

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Detalhes bibliográficos
Publicado no:J Leukoc Biol
Main Authors: Shrestha, Bishwas, You, Dahui, Saravia, Jordy, Siefker, David T., Jaligama, Sridhar, Lee, Greg I., Sallam, Asmaa A., Harding, Jeffrey N., Cormier, Stephania A.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Leukocyte Biology 2017
Assuntos:
Host Defense & Pathophysiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5470835/
https://ncbi.nlm.nih.gov/pubmed/28389622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.4A1216-536R
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