IL-4Rα on dendritic cells in neonates and Th2 immunopathology in respiratory syncytial virus infection

Respiratory syncytial virus (RSV) is one of the leading causes of bronchiolitis in children, and severe RSV infection early in life has been associated with asthma development. Using a neonatal mouse model, we have shown that down-regulation of IL-4 receptor α (IL-4Rα) with antisense oligonucleotide...

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Bibliographic Details
Published in:J Leukoc Biol
Main Authors: Shrestha, Bishwas, You, Dahui, Saravia, Jordy, Siefker, David T., Jaligama, Sridhar, Lee, Greg I., Sallam, Asmaa A., Harding, Jeffrey N., Cormier, Stephania A.
Format: Artigo
Language:Inglês
Published: Society for Leukocyte Biology 2017
Subjects:
Host Defense & Pathophysiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5470835/
https://ncbi.nlm.nih.gov/pubmed/28389622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.4A1216-536R
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