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Crawling with Virus: Translational Insights from a Neonatal Mouse Model on the Pathogenesis of Respiratory Syncytial Virus in Infants

The infant immune response to respiratory syncytial virus (RSV) remains incompletely understood. Here we review the use of a neonatal mouse model of RSV infection to mimic severe infection in human infants. We describe numerous age-specific responses, organized by cell type, observed in RSV-infected...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: You, Dahui, Saravia, Jordy, Siefker, David, Shrestha, Bishwas, Cormier, Stephania A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4702544/
https://ncbi.nlm.nih.gov/pubmed/26446604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01026-15
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