Limited Type I Interferons and Plasmacytoid Dendritic Cells during Neonatal Respiratory Syncytial Virus Infection Permit Immunopathogenesis upon Reinfection

Respiratory syncytial virus (RSV) infection is the number one cause of bronchiolitis in infants, yet no vaccines are available because of a lack of knowledge of the infant immune system. Using a neonatal mouse model, we previously revealed that mice initially infected with RSV as neonates develop Th...

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Detalhes bibliográficos
Main Authors: Cormier, Stephania A., Shrestha, Bishwas, Saravia, Jordy, Lee, Greg I., Shen, Li, DeVincenzo, John P., Kim, Young-in, You, Dahui
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136292/
https://ncbi.nlm.nih.gov/pubmed/24920801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00818-14
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