Osteoblast-specific overexpression of complement receptor C5aR1 impairs fracture healing

The anaphylatoxin receptor C5aR1 plays an important role not only in innate immune responses, but also in bone metabolism and fracture healing, being highly expressed on immune and bone cells, including osteoblasts and osteoclasts. C5aR1 induces osteoblast migration, cytokine generation and osteocla...

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Veröffentlicht in:PLoS One
Hauptverfasser: Bergdolt, Stephanie, Kovtun, Anna, Hägele, Yvonne, Liedert, Astrid, Schinke, Thorsten, Amling, Michael, Huber-Lang, Markus, Ignatius, Anita
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5470759/
https://ncbi.nlm.nih.gov/pubmed/28614388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0179512
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