Association of In Vivo [(18)F]AV-1451 Tau PET Imaging Results With Cortical Atrophy and Symptoms in Typical and Atypical Alzheimer Disease

IMPORTANCE: Previous postmortem studies have long demonstrated that neurofibrillary tangles made of hyperphosphorylated tau proteins are closely associated with Alzheimer disease clinical phenotype and neurodegeneration pattern. Validating these associations in vivo will lead to new diagnostic tools...

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Detalhes bibliográficos
Publicado no:JAMA Neurol
Main Authors: Xia, Chenjie, Makaretz, Sara J., Caso, Christina, McGinnis, Scott, Gomperts, Stephen N., Sepulcre, Jorge, Gomez-Isla, Teresa, Hyman, Bradley T., Schultz, Aaron, Vasdev, Neil, Johnson, Keith A., Dickerson, Bradford C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2017
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5470368/
https://ncbi.nlm.nih.gov/pubmed/28241163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2016.5755
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