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Stem cell models of Alzheimer’s disease: progress and challenges

A major challenge to our understanding of the molecular mechanisms of Alzheimer’s disease (AD) has been the lack of physiologically relevant in vitro models which capture the precise patient genome, in the cell type of interest, with physiological expression levels of the gene(s) of interest. Induce...

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Bibliografiske detaljer
Udgivet i:Alzheimers Res Ther
Main Authors: Arber, Charles, Lovejoy, Christopher, Wray, Selina
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5470327/
https://ncbi.nlm.nih.gov/pubmed/28610595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-017-0268-4
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