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Modeling Alzheimer's Disease with Induced Pluripotent Stem Cells: Current Challenges and Future Concerns
Alzheimer's disease (AD) is the most prevalent type of dementia and its pathology is characterized by deposition of extracellular β-amyloid plaques, intracellular neurofibrillary tangles, and extensive neuron loss. While only a few familial AD cases are due to mutations in three causative genes...
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| Publicado no: | Stem Cells Int |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Hindawi Publishing Corporation
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4895035/ https://ncbi.nlm.nih.gov/pubmed/27313629 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/7828049 |
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