An aberrant phase transition of stress granules triggered by misfolded protein and prevented by chaperone function

Stress granules (SG) are membrane‐less compartments involved in regulating mRNAs during stress. Aberrant forms of SGs have been implicated in age‐related diseases, such as amyotrophic lateral sclerosis (ALS), but the molecular events triggering their formation are still unknown. Here, we find that m...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:EMBO J
Autors principals: Mateju, Daniel, Franzmann, Titus M, Patel, Avinash, Kopach, Andrii, Boczek, Edgar E, Maharana, Shovamayee, Lee, Hyun O, Carra, Serena, Hyman, Anthony A, Alberti, Simon
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2017
Matèries:
Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5470046/
https://ncbi.nlm.nih.gov/pubmed/28377462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201695957
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars