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An aberrant phase transition of stress granules triggered by misfolded protein and prevented by chaperone function
Stress granules (SG) are membrane‐less compartments involved in regulating mRNAs during stress. Aberrant forms of SGs have been implicated in age‐related diseases, such as amyotrophic lateral sclerosis (ALS), but the molecular events triggering their formation are still unknown. Here, we find that m...
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| Publicado no: | EMBO J |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5470046/ https://ncbi.nlm.nih.gov/pubmed/28377462 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201695957 |
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