An aberrant phase transition of stress granules triggered by misfolded protein and prevented by chaperone function

Stress granules (SG) are membrane‐less compartments involved in regulating mRNAs during stress. Aberrant forms of SGs have been implicated in age‐related diseases, such as amyotrophic lateral sclerosis (ALS), but the molecular events triggering their formation are still unknown. Here, we find that m...

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Detaylı Bibliyografya
Yayımlandı:EMBO J
Asıl Yazarlar: Mateju, Daniel, Franzmann, Titus M, Patel, Avinash, Kopach, Andrii, Boczek, Edgar E, Maharana, Shovamayee, Lee, Hyun O, Carra, Serena, Hyman, Anthony A, Alberti, Simon
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2017
Konular:
Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5470046/
https://ncbi.nlm.nih.gov/pubmed/28377462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201695957
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