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Promiscuous interactions and protein disaggregases determine the material state of stress-inducible RNP granules

RNA-protein (RNP) granules have been proposed to assemble by forming solid RNA/protein aggregates or through phase separation into a liquid RNA/protein phase. Which model describes RNP granules in living cells is still unclear. In this study, we analyze P bodies in budding yeast and find that they h...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Kroschwald, Sonja, Maharana, Shovamayee, Mateju, Daniel, Malinovska, Liliana, Nüske, Elisabeth, Poser, Ina, Richter, Doris, Alberti, Simon
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4522596/
https://ncbi.nlm.nih.gov/pubmed/26238190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.06807
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