A novel Munc13-4/S100A10/annexin A2 complex promotes Weibel–Palade body exocytosis in endothelial cells

Endothelial cells respond to blood vessel injury by the acute release of the procoagulant von Willebrand factor, which is stored in unique secretory granules called Weibel–Palade bodies (WPBs). Stimulated WPB exocytosis critically depends on their proper recruitment to the plasma membrane, but facto...

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Publié dans:Mol Biol Cell
Auteurs principaux: Chehab, Tarek, Santos, Nina Criado, Holthenrich, Anna, Koerdt, Sophia N., Disse, Jennifer, Schuberth, Christian, Nazmi, Ali Reza, Neeft, Maaike, Koch, Henriette, Man, Kwun Nok M., Wojcik, Sonja M., Martin, Thomas F. J., van der Sluijs, Peter, Brose, Nils, Gerke, Volker
Format: Artigo
Langue:Inglês
Publié: The American Society for Cell Biology 2017
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5469611/
https://ncbi.nlm.nih.gov/pubmed/28450451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E17-02-0128
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