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Sortilin and retromer mediate retrograde transport of Glut4 in 3T3-L1 adipocytes

Sortilin is a multiligand sorting receptor responsible for the anterograde transport of lysosomal enzymes and substrates. Here we demonstrate that sortilin is also involved in retrograde protein traffic. In cultured 3T3-L1 adipocytes, sortilin together with retromer rescues Glut4 from degradation in...

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Bibliografiska uppgifter
I publikationen:Mol Biol Cell
Huvudupphovsmän: Pan, Xiang, Zaarur, Nava, Singh, Maneet, Morin, Peter, Kandror, Konstantin V.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The American Society for Cell Biology 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5469609/
https://ncbi.nlm.nih.gov/pubmed/28450454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-11-0777
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