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Sortilin and retromer mediate retrograde transport of Glut4 in 3T3-L1 adipocytes
Sortilin is a multiligand sorting receptor responsible for the anterograde transport of lysosomal enzymes and substrates. Here we demonstrate that sortilin is also involved in retrograde protein traffic. In cultured 3T3-L1 adipocytes, sortilin together with retromer rescues Glut4 from degradation in...
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| Publicado no: | Mol Biol Cell |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5469609/ https://ncbi.nlm.nih.gov/pubmed/28450454 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-11-0777 |
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