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Effect of lithium on ventricular remodelling in infarcted rats via the Akt/mTOR signalling pathways
Activation of phosphoinositide 3-kinase (PI3K)/Akt signalling is the molecular pathway driving physiological hypertrophy. As lithium, a PI3K agonist, is highly toxic at regular doses, we assessed the effect of lithium at a lower dose on ventricular hypertrophy after myocardial infarction (MI). Male...
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| Udgivet i: | Biosci Rep |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Portland Press Ltd.
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5469250/ https://ncbi.nlm.nih.gov/pubmed/28115595 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20160257 |
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