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Combinatorial gene regulation through kinetic control of the transcription cycle

Cells decide when, where, and to what level to express their genes by “computing” information from transcription factors (TFs) binding to regulatory DNA. How is the information contained in multiple TF binding sites integrated to dictate the rate of transcription? The dominant conceptual and quantit...

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Bibliografski detalji
Izdano u:Cell Syst
Glavni autori: Scholes, Clarissa, DePace, Angela H., Sánchez, Álvaro
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5469051/
https://ncbi.nlm.nih.gov/pubmed/28041762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2016.11.012
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