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Combinatorial gene regulation through kinetic control of the transcription cycle

Cells decide when, where, and to what level to express their genes by “computing” information from transcription factors (TFs) binding to regulatory DNA. How is the information contained in multiple TF binding sites integrated to dictate the rate of transcription? The dominant conceptual and quantit...

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Dades bibliogràfiques
Publicat a:Cell Syst
Autors principals: Scholes, Clarissa, DePace, Angela H., Sánchez, Álvaro
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5469051/
https://ncbi.nlm.nih.gov/pubmed/28041762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2016.11.012
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