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Information integration and energy expenditure in gene regulation

The quantitative concepts used to reason about gene regulation largely derive from bacterial studies. We show that this bacterial paradigm cannot explain the sharp expression of a canonical developmental gene in response to a regulating transcription factor (TF). In the absence of energy expenditure...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Estrada, Javier, Wong, Felix, DePace, Angela, Gunawardena, Jeremy
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4930556/
https://ncbi.nlm.nih.gov/pubmed/27368104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.06.012
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