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A framework for modelling gene regulation which accommodates non-equilibrium mechanisms

BACKGROUND: Gene regulation has, for the most part, been quantitatively analysed by assuming that regulatory mechanisms operate at thermodynamic equilibrium. This formalism was originally developed to analyse the binding and unbinding of transcription factors from naked DNA in eubacteria. Although w...

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Detalhes bibliográficos
Publicado no:BMC Biol
Main Authors: Ahsendorf, Tobias, Wong, Felix, Eils, Roland, Gunawardena, Jeremy
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4288563/
https://ncbi.nlm.nih.gov/pubmed/25475875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-014-0102-4
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