HDAC1 links early life stress to schizophrenia-like phenotypes

Schizophrenia is a devastating disease that arises on the background of genetic predisposition and environmental risk factors, such as early life stress (ELS). In this study, we show that ELS-induced schizophrenia-like phenotypes in mice correlate with a widespread increase of histone-deacetylase 1...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Bahari-Javan, Sanaz, Varbanov, Hristo, Halder, Rashi, Benito, Eva, Kaurani, Lalit, Burkhardt, Susanne, Anderson-Schmidt, Heike, Anghelescu, Ion, Budde, Monika, Stilling, Roman M., Costa, Joan, Medina, Juan, Dietrich, Detlef E., Figge, Christian, Folkerts, Here, Gade, Katrin, Heilbronner, Urs, Koller, Manfred, Konrad, Carsten, Nussbeck, Sara Y., Scherk, Harald, Spitzer, Carsten, Stierl, Sebastian, Stöckel, Judith, Thiel, Andreas, von Hagen, Martin, Zimmermann, Jörg, Zitzelsberger, Antje, Schulz, Sybille, Schmitt, Andrea, Delalle, Ivana, Falkai, Peter, Schulze, Thomas G., Dityatev, Alexander, Sananbenesi, Farahnaz, Fischer, André
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2017
Assuntos:
PNAS Plus
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5468618/
https://ncbi.nlm.nih.gov/pubmed/28533418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1613842114
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