HDAC1 links early life stress to schizophrenia-like phenotypes

Schizophrenia is a devastating disease that arises on the background of genetic predisposition and environmental risk factors, such as early life stress (ELS). In this study, we show that ELS-induced schizophrenia-like phenotypes in mice correlate with a widespread increase of histone-deacetylase 1...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Bahari-Javan, Sanaz, Varbanov, Hristo, Halder, Rashi, Benito, Eva, Kaurani, Lalit, Burkhardt, Susanne, Anderson-Schmidt, Heike, Anghelescu, Ion, Budde, Monika, Stilling, Roman M., Costa, Joan, Medina, Juan, Dietrich, Detlef E., Figge, Christian, Folkerts, Here, Gade, Katrin, Heilbronner, Urs, Koller, Manfred, Konrad, Carsten, Nussbeck, Sara Y., Scherk, Harald, Spitzer, Carsten, Stierl, Sebastian, Stöckel, Judith, Thiel, Andreas, von Hagen, Martin, Zimmermann, Jörg, Zitzelsberger, Antje, Schulz, Sybille, Schmitt, Andrea, Delalle, Ivana, Falkai, Peter, Schulze, Thomas G., Dityatev, Alexander, Sananbenesi, Farahnaz, Fischer, André
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2017
Soggetti:
PNAS Plus
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5468618/
https://ncbi.nlm.nih.gov/pubmed/28533418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1613842114
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