Selective regulation of Notch ligands during angiogenesis is mediated by vimentin

Notch signaling is a key regulator of angiogenesis, in which sprouting is regulated by an equilibrium between inhibitory Dll4-Notch signaling and promoting Jagged-Notch signaling. Whereas Fringe proteins modify Notch receptors and strengthen their activation by Dll4 ligands, other mechanisms balanci...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Antfolk, Daniel, Sjöqvist, Marika, Cheng, Fang, Isoniemi, Kimmo, Duran, Camille L., Rivero-Muller, Adolfo, Antila, Christian, Niemi, Rasmus, Landor, Sebastian, Bouten, Carlijn V. C., Bayless, Kayla J., Eriksson, John E., Sahlgren, Cecilia M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5468602/
https://ncbi.nlm.nih.gov/pubmed/28533359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1703057114
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