Vimentin regulates Notch signaling strength and arterial remodeling in response to hemodynamic stress

The intermediate filament (IF) cytoskeleton has been proposed to regulate morphogenic processes by integrating the cell fate signaling machinery with mechanical cues. Signaling between endothelial cells (ECs) and vascular smooth muscle cells (VSMCs) through the Notch pathway regulates arterial remod...

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Publicat a:Sci Rep
Autors principals: van Engeland, Nicole C. A., Suarez Rodriguez, Freddy, Rivero-Müller, Adolfo, Ristori, Tommaso, Duran, Camille L., Stassen, Oscar M. J. A., Antfolk, Daniel, Driessen, Rob C. H., Ruohonen, Saku, Ruohonen, Suvi T., Nuutinen, Salla, Savontaus, Eriika, Loerakker, Sandra, Bayless, Kayla J., Sjöqvist, Marika, Bouten, Carlijn V. C., Eriksson, John E., Sahlgren, Cecilia M.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6712036/
https://ncbi.nlm.nih.gov/pubmed/31455807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48218-w
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