NLRC3 is an inhibitory sensor of PI3K–mTOR pathways in cancer

Nucleotide-binding domain, leucine-rich repeat containing proteins (NLRs) belong to a large family of cytoplasmic sensors which regulate an extraordinarily diverse range of biological functions. NLRs contribute to immunity against infectious diseases, however, dysregulation of their functional activ...

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Bibliografiska uppgifter
I publikationen:Nature
Huvudupphovsmän: Karki, Rajendra, Man, Si Ming, Malireddi, R.K. Subbarao, Kesavardhana, Sannula, Zhu, Qifan, Burton, Amanda R., Sharma, Bhesh Raj, Qi, Xiaopeng, Pelletier, Stephane, Vogel, Peter, Rosenstiel, Philip, Kanneganti, Thirumala-Devi
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2016
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5468516/
https://ncbi.nlm.nih.gov/pubmed/27951586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature20597
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