Cathepsin L Promotes Vascular Intimal Hyperplasia after Arterial Injury

The inflammatory pathways that drive the development of intimal hyperplasia (IH) following arterial injury are not fully understood. We hypothesized that the lysosomal cysteine protease cathepsin L activates processes leading to IH after arterial injury. Using a mouse model of wire-induced carotid a...

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Detalhes bibliográficos
Publicado no:Mol Med
Main Authors: Cai, Jingjing, Zhong, Hua, Wu, Jinze, Chen, Rui-Fang, Yang, Huan, Al-Abed, Yousef, Li, Ying, Li, Xiaohui, Jiang, Weihong, Montenegro, Marcelo F, Yuan, Hong, Billiar, Timothy R, Chen, Alex F
Formato: Artigo
Idioma:Inglês
Publicado em: Feinstein Institute for Medical Research 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5468173/
https://ncbi.nlm.nih.gov/pubmed/28332696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2016.00222
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