Viral genetic variation accounts for a third of variability in HIV-1 set-point viral load in Europe

HIV-1 set-point viral load—the approximately stable value of viraemia in the first years of chronic infection—is a strong predictor of clinical outcome and is highly variable across infected individuals. To better understand HIV-1 pathogenesis and the evolution of the viral population, we must quant...

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Publicado no:PLoS Biol
Main Authors: Blanquart, François, Wymant, Chris, Cornelissen, Marion, Gall, Astrid, Bakker, Margreet, Bezemer, Daniela, Hall, Matthew, Hillebregt, Mariska, Ong, Swee Hoe, Albert, Jan, Bannert, Norbert, Fellay, Jacques, Fransen, Katrien, Gourlay, Annabelle J., Grabowski, M. Kate, Gunsenheimer-Bartmeyer, Barbara, Günthard, Huldrych F., Kivelä, Pia, Kouyos, Roger, Laeyendecker, Oliver, Liitsola, Kirsi, Meyer, Laurence, Porter, Kholoud, Ristola, Matti, van Sighem, Ard, Vanham, Guido, Berkhout, Ben, Kellam, Paul, Reiss, Peter, Fraser, Christophe
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5467800/
https://ncbi.nlm.nih.gov/pubmed/28604782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2001855
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