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How effectively can HIV phylogenies be used to measure heritability?

Background and objectives: The severity of HIV-1 infection, measured by set-point viral load (SPVL), is highly variable between individuals. Its heritability between infections quantifies the control the pathogen genotype has over disease severity. Heritability estimates vary widely between studies,...

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Autors principals: Shirreff, George, Alizon, Samuel, Cori, Anne, Günthard, Huldrych F., Laeyendecker, Oliver, van Sighem, Ard, Bezemer, Daniela, Fraser, Christophe
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3850537/
https://ncbi.nlm.nih.gov/pubmed/24481201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emph/eot019
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