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Virulence and pathogenesis of HIV-1 infection: an evolutionary perspective

Why some individuals develop AIDS rapidly whereas others remain healthy without treatment for many years remains a central question of HIV research. An evolutionary perspective reveals an apparent conflict between two levels of selection on the virus. On the one hand, there is rapid evolution of the...

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Detalhes bibliográficos
Publicado no:Science
Main Authors: Fraser, Christophe, Lythgoe, Katrina, Leventhal, Gabriel E., Shirreff, George, Hollingsworth, T. Déirdre, Alizon, Samuel, Bonhoeffer, Sebastian
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5034889/
https://ncbi.nlm.nih.gov/pubmed/24653038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1243727
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