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High Heritability Is Compatible with the Broad Distribution of Set Point Viral Load in HIV Carriers

Set point viral load in HIV patients ranges over several orders of magnitude and is a key determinant of disease progression in HIV. A number of recent studies have reported high heritability of set point viral load implying that viral genetic factors contribute substantially to the overall variatio...

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Bibliografske podrobnosti
izdano v:PLoS Pathog
Main Authors: Bonhoeffer, Sebastian, Fraser, Christophe, Leventhal, Gabriel E.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4450065/
https://ncbi.nlm.nih.gov/pubmed/25658741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004634
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