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Tumor RAS Gene Expression Levels Are Influenced by the Mutational Status of RAS Genes and Both Upstream and Downstream RAS Pathway Genes

The 3 human RAS genes play pivotal roles regulating proliferation, differentiation, and survival in normal cells and become mutated in 15% to 20% of all human tumors and amplified in many others. In this report, we examined data from The Cancer Genome Atlas to investigate the relationship between RA...

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Dettagli Bibliografici
Pubblicato in:Cancer Inform
Autori principali: Stephens, Robert M, Yi, Ming, Kessing, Bailey, Nissley, Dwight V, McCormick, Frank
Natura: Artigo
Lingua:Inglês
Pubblicazione: SAGE Publications 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5467702/
https://ncbi.nlm.nih.gov/pubmed/28634423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1176935117711944
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