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Structural basis of HypK regulating N-terminal acetylation by the NatA complex

In eukaryotes, N-terminal acetylation is one of the most common protein modifications involved in a wide range of biological processes. Most N-acetyltransferase complexes (NATs) act co-translationally, with the heterodimeric NatA complex modifying the majority of substrate proteins. Here we show tha...

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Publicat a:Nat Commun
Autors principals: Weyer, Felix Alexander, Gumiero, Andrea, Lapouge, Karine, Bange, Gert, Kopp, Jürgen, Sinning, Irmgard
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5467210/
https://ncbi.nlm.nih.gov/pubmed/28585574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15726
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