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Molecular basis for N-terminal acetylation by human NatE and its modulation by HYPK
The human N-terminal acetyltransferase E (NatE) contains NAA10 and NAA50 catalytic, and NAA15 auxiliary subunits and associates with HYPK, a protein with intrinsic NAA10 inhibitory activity. NatE co-translationally acetylates the N-terminus of half the proteome to mediate diverse biological processe...
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| Опубликовано в: : | Nat Commun |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group UK
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7010799/ https://ncbi.nlm.nih.gov/pubmed/32042062 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-14584-7 |
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