The Chaperone-Like Protein HYPK Acts Together with NatA in Cotranslational N-Terminal Acetylation and Prevention of Huntingtin Aggregation

The human NatA protein N(α)-terminal-acetyltransferase complex is responsible for cotranslational N-terminal acetylation of proteins with Ser, Ala, Thr, Gly, and Val N termini. The NatA complex is composed of the catalytic subunit hNaa10p (hArd1) and the auxiliary subunit hNaa15p (hNat1/NATH). Using...

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Main Authors: Arnesen, Thomas, Starheim, Kristian K., Van Damme, Petra, Evjenth, Rune, Dinh, Huyen, Betts, Matthew J., Ryningen, Anita, Vandekerckhove, Joël, Gevaert, Kris, Anderson, Dave
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849469/
https://ncbi.nlm.nih.gov/pubmed/20154145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01199-09
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