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Targeting GPCR-Gβγ-GRK2 signaling as a novel strategy for treating cardiorenal pathologies

The pathologic crosstalk between the heart and kidney is known as cardiorenal syndrome (CRS). While the specific mechanisms underlying this crosstalk remain poorly understood, CRS is associated with exacerbated dysfunction of either or both organs and reduced survival. Maladaptive fibrotic remodelin...

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Dades bibliogràfiques
Publicat a:Biochim Biophys Acta
Autors principals: Rudomanova, Valeria, Blaxall, Burns C.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5466897/
https://ncbi.nlm.nih.gov/pubmed/28130200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2017.01.020
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